The study of the manuscript annotations has now a dignity. But it remains the conceptual difficulty to find an exact position to the printed book with annotations. The printed books are normally considered a set of the multiple copies. The description of manuscript annotations has to inform, in synthetic manner, on their placement in the book and in the page, on their paleographic, linguistic and cultural characteristic. A photographic reproduction of at least an example appear necessary. Different scholars have different approaches to the manuscript annotations, in accordance with the differences in studies that use them.